IOWA CITY — Six years ago Paul Harding was just another graduate of the Iowa Writers’ Workshop with a quiet little novel he hoped to publish. He sent copies of the manuscript, in which he had intertwined the deathbed memories of a New England clock repairer with episodes about the dying man’s father, to a handful of agents and editors in New York. Soon after, the rejection letters started to roll in.

“They would lecture me about the pace of life today,” Mr. Harding said last week over lunch at a diner in this college town, where he is now teaching at the workshop. “It was, ‘Where are the car chases?’ ” he said, recalling the gist of the letters. “ ‘Nobody wants to read a slow, contemplative, meditative, quiet book.’ ”

His manuscript languished in a desk drawer for nearly three years. But in perhaps the most dramatic literary Cinderella story of recent memory, Mr. Harding, 42, not only eventually found a publisher — the tiny Bellevue Literary Press — for the novel, “Tinkers,” he also went on to win the Pulitzer Prize for fiction last week. Within an hour of the Pulitzer announcement, Random House sent out a news release boasting of the two-book deal it had signed with Mr. Harding late in 2009. A few days later the Guggenheim Foundation announced he had received one of its prestigious fellowships.

The early rejection “was funny at the time,” Mr. Harding said. “And even funnier now.” Mr. Harding, a onetime drummer for a rock band, is far too discreet to name any of the agents or editors who wouldn’t touch his work a few years ago.

But he is quick to praise those who helped “Tinkers” become a darling of the independent bookstore circuit, including Erika Goldman, the editorial director of Bellevue, whom Mr. Harding described as a “deeply empathetic reader”; Lise Solomon, a sales representative in Northern California for Consortium, the book’s distributor, who passionately advocated for the novel with booksellers; and the booksellers and critics who embraced the book early on.

Although “Tinkers” sunk under the radar in some quarters (including The New York Times, which did not review it), it made several year-end best lists, including NPR’s best debut fiction and The New Yorker magazine’s list of reviewers’ favorites. According to Nielsen Bookscan, which tracks about 70 percent of retail sales, “Tinkers” sold 7,000 copies before the Pulitzer announcement.

In classes at Iowa Mr. Harding has become an instant celebrity, of course, but also, a reassurance. Marilynne Robinson, the Pulitzer Prize-winning author of “Gilead,” Mr. Harding’s former teacher and now a friend, said last week in her workshop office that she had already repeated Mr. Harding’s story several times.

“One of the problems I have is making my students believe that they can write something that satisfies their definition of good, and they don’t have to calculate the market,” Ms. Robinson said. “Now that I have the Paul anecdote, they will believe me more.”